Environmental Impact on Reproductive Health: Can Biomarkers Offer Any Help?

Bhargava, Arpit; Pathak, Neelam; Sharma, Radhey; Lohiya, Nirmal; Mishra, Pradyumna

Environmental Impact on Reproductive Health: Can Biomarkers Offer Any Help?

Authors

Arpit Bhargava ¹

Neelam Pathak ²

Radhey Sharma ³

Nirmal Lohiya ⁴

Pradyumna Mishra ⁵

¹ School of Biological Sciences, Dr. Harisingh Gour Central University, Sagar, India

² School of Biological Sciences, Dr. Harisingh Gour Central University, Sagar, India; Centre for Advanced Studies in Zoology, University of Rajasthan, Jaipur, India

³ Division of Reproductive Biology, Maternal and Child Health, Indian Council of Medical Research, New Delhi, India

⁴ Centre for Advanced Studies in Zoology, University of Rajasthan, Jaipur, India

⁵ School of Biological Sciences, Dr. Harisingh Gour Central University, Sagar, India; Department of Molecular Biology, National Institute for Research in Environmental Health, Indian Council of Medical Research, Bhopal, India

Mishra PK, Dabadghao S, Modi GK, Desikan P, Jain A, Mittra I, et al. In utero exposure to methyl isocyanate in the Bhopal gas disaster: evidence of persisting hyperactivation of immune system two decades later. Occup Environ Med. 2009;66(4):279.

Bunkar N, Pathak N, Lohiya NK, Mishra PK. Epigenetics: A key paradigm in reproductive health. Clin Exp Reprod Med. 2016;43(2):59-81.

Mishra PK. A pragmatic & translational approach of human biomonitoring to methyl isocyanate exposure in Bhopal. Indian J Med Res. 2012;135(4):479-84.

Caserta D, Di Segni N, Mallozzi M, Giovanale V, Mantovani A, Marci R, et al. Bisphenol A and the female reproductive tract: an overview of recent laboratory evidence and epidemiological studies. Reprod Biol Endocrinol. 2014;12:37.

Takeuchi T, Tsutsumi O, Ikezuki Y, Kamei Y, Osuga Y, Fujiwara T, et al. Elevated serum bisphenol A levels under hyperandrogenic conditions may be caused by decreased UDP-glucuronosyl transferase activity. Endocr J. 2006;53(4):485-91.

Taylor TH, Gitlin SA, Patrick JL, Crain JL, Wilson JM, Griffin DK. The origin, mechanisms, incidence and clinical consequences of chromosomal mosaicism in humans. Hum Reprod Update. 2014;20(4):571-81.

Block ML, Calderón-Garcidueñas L. Air pollution: mechanisms of neuroinflammation and CNS disease. Trends Neurosci. 2009;32(9):506-16.

Saenen ND, Plusquin M, Bijnens E, Janssen BG, Gyselaers W, Cox B, et al. In utero fine particle air pollution and placental expression of genes in the brain-derived neurotrophic factor signaling pathway: An environage birth cohort study. Environ Health Perspect. 2015;123(8):834-40.

Heederik D, von Mutius E. Does diversity of environmental microbial exposure matter for the occurrence of allergy and asthma? J Allergy Clin Immunol. 2012;130(1):44-50.

Breton CV, Byun HM, Wang X, Salam MT, Siegmund K, Gilliland FD. DNA methylation in the arginase-nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma. Am J Respir Crit Care Med. 2011;184(2):191-7.

Habermann M, Gouveia N. Socioeconomic position and low birth weight among mothers exposed to traffic-related air pollution. PLoS One. 2014;9(11):e113900.

Cole LA, Kardana A, Seifer DB, Bohler HC Jr. Urine hCG beta-subunit core fragment, a sensitive test for ectopic pregnancy. J Clin Endocrinol Metab. 1994;78(2):497-9.

Belo L, Santos-Silva A, Rumley A, Lowe G, Pereira-Leite L, Quintanilha A, et al. Elevated tissue plasminogen activator as a potential marker of endothelial dysfunction in pre-eclampsia: correlation with proteinuria. BJOG. 2002;109(11):1250-5.

Wallace C, Smyth DJ, Maisuria-Armer M, Walker NM, Todd JA, Clayton DG. The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes. Nat Genet. 2010;42(1):68-71.

Choufani S, Shuman C, Weksberg R. Molecular findings in Beckwith-Wiedemann syndrome. Am J Med Genet C Semin Med Genet. 2013;163C(2):131-40.

Talens RP, Jukema JW, Trompet S, Kremer D, Westendorp RG, Lumey LH, et al. Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction. Int J Epidemiol. 2012;41(1):106-15.

Herberth G, Bauer M, Gasch M, Hinz D, Röder S, Olek S, et al. Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers. J Allergy Clin Immunol. 2014;133(2):543-50.