Journal of Reproduction & Infertility

Journal of Reproduction & Infertility

Evaluation of L-Carnitine Potential in Improvement of Male Fertility

Authors
Leila Kooshesh 1
Zohre Nateghian 2
Elham Aliabadi 3
1 Department of Genetics, Fars Academic Center for Education, Culture and Research, ACECR, Shiraz, Iran
2 Islamic Azad University of Isfahan (Khorasgan) Branch, Isfahan, Iran
3 Department of Anatomy, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
10.18502/jri.v24i2.12491
Abstract
L-carnitine, through its antioxidant potential, plays a significant role in reducing ROS production in male genital tract; therefore, fundamental improvements in spermatogenesis process and sperm structural and functional parameters in seminal plasma can be observed by treatment with L-carnitine. A literature search was performed using PubMed (including Medline) from the database earliest inception to 2021. Eligibility criteria included studies on protective effects of L-carnitine against damages to the male reproductive system. Based on the findings of the current study, L-carnitine has an effective potential to protect testis and improve conventional and functional sperm parameters against ROS-induced damages by sperm cryopreservation, busulfan treatment, and radiation.
Keywords
busulfan
L
Carnitine
Male Fertility
Radiation
Sperm cryopreservation
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Journal of Reproduction & Infertility
Volume 24, Issue 2
Spring 2023
Pages 69-84