Journal of Reproduction & Infertility

Journal of Reproduction & Infertility

Correlation between asymptomatic urethritis with bacteriospermia in seminal plasma of fertile and infertile men

Authors
Mohammad Bagher Khalili 1
Mohammad Ali Khalili 2
1 Microbiology Department, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2 Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract
Urogenital infection can influence the fertilization potential of the spermatozoa, which may lead to male infertility. The symptomatic urethiritis can change the semen parameters, however the role of asymptomatic urethirtis in fertility is still obscure. In this descriptive investigation, a total of 148 samples from urethra and semen of fertile as well as 146 samples from urethra and semen of infertiles men were examined for the presence of 5 bacterial species including streptococcus group A., Entercoccus, E.coli, coagulase positive and negative Staphylococcus. The rate of infection of urethra and semen of fertile men were 49.22% and 29.05%, respectively. The aforementioned rates were 34.9% and 60.27% for infertile men. The seminal infection was significantly different between two groups of fertile and infertile (p < 0.01). The results showed that the most common pathogen in semen of fertile and infertile men was Entrococcus with prevalence of 32.60% (14 cases), and 42% (37 cases), respectively. A total of 90 out of 131 samples contaminated with bacteria showed high rate of Leuckocytes (pyospermia). The remaining 41 infected samples lacked or had low number of leuckocytes. In conclusion, bacteriospermia is significantly higher in seminal samples of infertile than fertile men (p < 0.01). Therefore, the pathogens involved in urethritis may be involved in male infertility. In addition, seminal culture is necessary for detection of bacteria presence in the semen, and thus it is important to note that presence or absence of Leukocyte in semen may not represent the urogenital infection.
Keywords
Bacteriospermia
Male infertility
Pyospermy
Semen
Urethritis
Urogenital infection
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Journal of Reproduction & Infertility
Volume 3, Issue 4
Autumn 2002
Pages 21-28