Journal of Reproduction & Infertility

Journal of Reproduction & Infertility

Determining the relation between non-fasting serum leptin- BMI ratio and follicular fluid leptin to ART outcomes

Authors
Leili Safdarian 1
Elaheh Mossayebi 1
Ebrahim Djavadi 2
Mohammad Bagher Larijani 2
Ramin Heshmat 2
Afsaneh Khademi 1
Ashraf Alyasin 1
Marzieh Agha Hossinei 1
1 Infertility Treatment Ward, Shariati Hospital, Faculty of Medicine, Tehran University of Medical Sciences & Health Services University, Tehran, Iran
2 Endocrinology and Metabolism Research Center (EMRC), Tehran University of Medical Sciences, Tehran, Iran
Abstract
Introduction: Considering the economical and psychological burden of assisted reproductive technologies (ART), finding factors predicting ART results is of great value. So this study was undertaken to evaluate whether serum and follicular and serum leptin to body mass index (BMI) are predictive of ART outcomes. Materials & Methods: 99 non-polycystic ovary patients from the body of patients referring to infertility ward of Shariati Hospital, from April to September 2005, were selected and underwent the long protocol of GnRH agonist ovarian hyperstimulation. Serum leptin was measured on the 3rd day of menstrual cycle. Follicular fluid (FF) was collected on the day of oocyte retrieval. The serum and follicular fluid leptin levels were determined by ELISA. Mean the levels of serum and follicular fluid leptin and leptin to BMI ratios were compared in pregnant and nonpregnant women, using SPSS software, student t-test. P-values
Keywords
Assisted Reproductive Techniques
BMI
COH
FF
Infertility
leptin
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Journal of Reproduction & Infertility
Volume 7, Issue 2
Summer 2006
Pages 111-116